BDBM50054500 CHEMBL140646::{(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohexylcarbamoyl)-methyl]-2-oxo-piperidin-3-yl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@H]1CCCN(CC(=O)N[C@H]2CCCC(C2O)C(N)=N)C1=O

InChI Key InChIKey=JQIGGADUNOGQQW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054500   

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054500({(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohexylc...)
Affinity DataIC50: 1.46E+3nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054500({(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohexylc...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054500({(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohexylc...)
Affinity DataIC50: 1.68E+4nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed