BDBM50054154 8-[4-spiro[3,4-dihydro-2H-chromene-3,2'-(tetrahydro-1'H-pyrrole)]-1-ylbutyl]-8-azaspiro[4.5]decane-7,9-dione::CHEMBL135952

SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCCC11COc2ccccc2C1

InChI Key InChIKey=HOYFSXBLFWVLAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054154   

Target5-hydroxytryptamine receptor 1B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50054154(8-[4-spiro[3,4-dihydro-2H-chromene-3,2'-(tetrahydr...)
Affinity DataIC50: 3.80E+3nMAssay Description:Binding affinity to 5-HT1B receptors using rat cortex+striatum + globus pallidus,[3H]-5-OH-tryptamine, and serotonin for NSBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50054154(8-[4-spiro[3,4-dihydro-2H-chromene-3,2'-(tetrahydr...)
Affinity DataIC50: 178nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed