BDBM50054148 5-methoxyspiro[3,4-dihydro-2H-chromene-3,2'-(tetrahydro-1'H-pyrrole)]-5'-one::CHEMBL132970

SMILES COc1cccc2OCC3(CCC(=O)N3)Cc12

InChI Key InChIKey=NRITVOYDKDGUCC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054148   

Target5-hydroxytryptamine receptor 1B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50054148(5-methoxyspiro[3,4-dihydro-2H-chromene-3,2'-(tetra...)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to 5-HT1B receptors using rat cortex+striatum + globus pallidus,[3H]-5-OH-tryptamine, and serotonin for NSBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50054148(5-methoxyspiro[3,4-dihydro-2H-chromene-3,2'-(tetra...)
Affinity DataIC50: 4.37E+3nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed