BDBM50054117 1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl)piperidine::1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperidine::CHEMBL134607

SMILES COc1cccc2C(CCCN3CCCCC3)CCCc12

InChI Key InChIKey=OECXRJKGMSAVLR-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50054117   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50054117(1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  3.38nMAssay Description:Displacement of [3H](+)-pentazocine ((+)-[2S-(2R,6R,11R)]-1,2,3,4,5,6-hexahydro-6,11-dimethyl- 3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocine- 8-ol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50054117(1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  11.1nMAssay Description:Displacement of [3H](+/-)-emopamil from EBP in Dunkin guinea pig liver membrane by radioreceptor binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50054117(1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  18.2nMAssay Description:Displacement of [3H](+/-)-pentazocine from sigma 1 receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50054117(1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi: >1.43E+3nMAssay Description:Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50054117(1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi: >1.85E+3nMAssay Description:Binding affinity was tested on Dopamine receptor D2 using radioligand [3H]spiroperidolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed