BDBM50054095 1-{4-[4-(4-amino-1-quinoliniumylmethyl)phenethyl]benzyl}-4-quinoliniumamine::1.1'-[ethylenebis(benzene-1,4-diylmethylene)]bis(4-aminoquinolinium)::CHEMBL362961::CHEMBL429017

SMILES [NH2+]=c1ccn(Cc2ccc(CCc3ccc(Cn4ccc(=[NH2+])c5ccccc45)cc3)cc2)c2ccccc12

InChI Key InChIKey=SSYLZSFCNUGCEN-UHFFFAOYSA-P

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50054095   

TargetCholine kinase alpha(Human)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50054095(CHEMBL429017 | CHEMBL362961 | 1-{4-[4-(4-amino-1-q...)
Affinity DataIC50: 8.00E+4nMAssay Description:Ex vivo inhibitory concentration against human choline kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50054095(CHEMBL429017 | CHEMBL362961 | 1-{4-[4-(4-amino-1-q...)
Affinity DataIC50: 410nMAssay Description:Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetAcetylcholinesterase(Bovine)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50054095(CHEMBL429017 | CHEMBL362961 | 1-{4-[4-(4-amino-1-q...)
Affinity DataIC50: 672nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50054095(CHEMBL429017 | CHEMBL362961 | 1-{4-[4-(4-amino-1-q...)
Affinity DataIC50: 620nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandPNGBDBM50054095(CHEMBL429017 | CHEMBL362961 | 1-{4-[4-(4-amino-1-q...)
Affinity DataIC50: 410nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed