BDBM50053603 1N-amino(immino)methyl-3-trifluoromethylaniline::CHEMBL44236::N-(3-Trifluoromethyl-phenyl)-guanidine::N-[3-(trifluoromethyl)phenyl]guanidine

SMILES [#7]\[#6](-[#7])=[#7]\c1cccc(c1)C(F)(F)F

InChI Key InChIKey=HHRUCLOFXWEDAH-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50053603   

Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50053603(N-(3-Trifluoromethyl-phenyl)-guanidine | N-[3-(tri...)
Affinity DataKi:  5.70E+3nMAssay Description:Compound was tested for the inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor expressed in NG 108-15 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50053603(N-(3-Trifluoromethyl-phenyl)-guanidine | N-[3-(tri...)
Affinity DataKi:  1.07E+7nMAssay Description:Inhibition against TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50053603(N-(3-Trifluoromethyl-phenyl)-guanidine | N-[3-(tri...)
Affinity DataKi:  4.19E+5nMAssay Description:Inhibition against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50053603(N-(3-Trifluoromethyl-phenyl)-guanidine | N-[3-(tri...)
Affinity DataKi:  4.19E+5nMAssay Description:Inhibition against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50053603(N-(3-Trifluoromethyl-phenyl)-guanidine | N-[3-(tri...)
Affinity DataKi:  1.07E+7nMAssay Description:log1/Ki value was calculated against TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50053603(N-(3-Trifluoromethyl-phenyl)-guanidine | N-[3-(tri...)
Affinity DataKi: <1.00E+7nMAssay Description:Inhibition against human plasmin was determined at 0.5 mMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed