BDBM50053519 7-[3-(3-Hydroxy-6,8-dioxa-bicyclo[3.2.1]oct-3-yl)-benzyloxy]-4-phenyl-3H-naphtho[2,3-c]furan-1-one::CHEMBL129253

SMILES OC1(CC2COC(C1)O2)c1cccc(COc2ccc3c(c4COC(=O)c4cc3c2)-c2ccccc2)c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053519   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50053519(7-[3-(3-Hydroxy-6,8-dioxa-bicyclo[3.2.1]oct-3-yl)-...)
Affinity DataIC50: 240nMAssay Description:Potency to inhibit oxidation of arachidonic acid by recombinant human 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50053519(7-[3-(3-Hydroxy-6,8-dioxa-bicyclo[3.2.1]oct-3-yl)-...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human 5-LO expressed in Sf9 cells by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed