BDBM50053430 4-[3-Cyclopropyl-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-pyridine::CHEMBL126023

SMILES Fc1ccc(cc1)-c1ncn(C2CC2)c1-c1ccncc1

InChI Key InChIKey=VXSHGJJXHHEQII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053430   

TargetProstaglandin G/H synthase 1(Sheep)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053430(4-[3-Cyclopropyl-5-(4-fluoro-phenyl)-3H-imidazol-4...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory concentration against Prostaglandin H2 synthase 1 (PGHS-1) from ram seminal vesicleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053430(4-[3-Cyclopropyl-5-(4-fluoro-phenyl)-3H-imidazol-4...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibitory concentration against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed