BDBM50053313 CHEMBL3330241::US11370770, Compound 6h

SMILES NC(=O)c1cccc(c1)-c1n[nH]c2cccc(Cl)c12

InChI Key InChIKey=ZTCSCMJRLGYLPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053313   

TargetDual specificity protein kinase TTK(Human)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50053313(CHEMBL3330241 | US11370770, Compound 6h)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of GST-fused full length human TTK compound pre-incubated for 15 mins prior ATP addition by MBP-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

US Patent
LigandPNGBDBM50053313(CHEMBL3330241 | US11370770, Compound 6h)
Affinity DataIC50: 1.30E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent