BDBM50053194 CHEMBL301956::[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-ylmethyl]-dimethyl-amine

SMILES CN(C)Cc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12

InChI Key InChIKey=SPLFGEFBTYQRPO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50053194   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50053194([5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-ylmethyl]...)
Affinity DataIC50: 11.0nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50053194([5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-ylmethyl]...)
Affinity DataIC50: 12nMAssay Description:Binding affinity to serotonin 5-hydroxytryptamine 2A receptors using a radioligand [3H]ketanserin binding assay in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50053194([5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-ylmethyl]...)
Affinity DataIC50: 18nMAssay Description:Binding affinity to the alpha-1 adrenergic receptor using a radioligand [3H]prazosin binding assay in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50053194([5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-ylmethyl]...)
Affinity DataIC50: 19nMAssay Description:Binding affinity to dopamine receptor D2 using a [3H]-spiperone binding assay in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50053194([5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-ylmethyl]...)
Affinity DataIC50: 11nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed