BDBM50052869 (R)-6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL25924

SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2ccccc2)c-31

InChI Key InChIKey=TVYKKVMHDGSECW-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50052869   

Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052869(6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[...)
Affinity DataKi:  1.80nMAssay Description:In vitro displacement of [3H]8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052869(6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[...)
Affinity DataKi:  1.80nMAssay Description:In vitro ability to inhibit [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052869(6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052869(6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052869(6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052869(6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[...)
Affinity DataKi:  9.78nMAssay Description:Displacement of [3H]5-HT from rat 5-hydroxytryptamine 7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50052869(6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[...)
Affinity DataKi:  9.80nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052869(6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[...)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]5-HT from rat 5-HT7 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052869(6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[...)
Affinity DataKi:  233nMAssay Description:Displacement of [3H]raclopride from human Dopamine receptor D2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052869(6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[...)
Affinity DataKi:  233nMAssay Description:Displacement of [3H]raclopride from human dopamine receptor D2A expressed in mouse Ltk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052869(6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[...)
Affinity DataKi:  3.63E+3nMAssay Description:Affinity for dopamine receptor D1 binding measured by competition against [3H]-SCH- 23390 to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed