BDBM50052750 CHEMBL115470::Dimethyl-carbamic acid 5-(4-azido-phenyl)-6-oxa-10b-aza-benzo[e]azulen-4-yl ester

SMILES CN(C)C(=O)OC1=C(Oc2ccccc2-n2cccc12)c1ccc(cc1)N=[N+]=[N-]

InChI Key InChIKey=FMPKONDQOQSCTG-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50052750   

TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50052750(Dimethyl-carbamic acid 5-(4-azido-phenyl)-6-oxa-10...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of binding of [3H]-PK 11195 to peripheral-type benzodiazepine receptor (PBR) from rat cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50052750(Dimethyl-carbamic acid 5-(4-azido-phenyl)-6-oxa-10...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity against peripheral-type benzodiazepine receptor (PBR) from rat cortex homogenate using [3H]-PK 11195 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50052750(Dimethyl-carbamic acid 5-(4-azido-phenyl)-6-oxa-10...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]-Ro- 5-4864 from rat adrenal peripheral-type benzodiazepine receptor (PBR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50052750(Dimethyl-carbamic acid 5-(4-azido-phenyl)-6-oxa-10...)
Affinity DataKi:  4.80nMAssay Description:Displacement [3H]-PK 11195 from rat adrenal peripheral-type benzodiazepine receptor (PBR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed