BDBM50052573 5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amide::CHEMBL26426

SMILES COc1cccc2C(CCCc12)C(=O)NCCN1CCN(CC1)c1ccccc1OC

InChI Key InChIKey=CPGVFFIAFKTJQY-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50052573   

Target5-hydroxytryptamine receptor 1A(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50052573(5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxy...)
Affinity DataIC50: 35nMAssay Description:Binding affinity against serotonin 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50052573(5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxy...)
Affinity DataIC50: 448nMAssay Description:Binding affinity against Dopamine receptor D2 in rat striatal membrane using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50052573(5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxy...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]YM-09151-2 from human Dopamine receptor D4.2 expressed in baculovirus Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50052573(5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxy...)
Affinity DataKi:  142nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(2) dopamine receptor(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50052573(5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxy...)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]spiperone from Dopamine receptor D2 of rat corpora striata synaptic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article