BDBM50052563 3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propionamide::CHEMBL28063::N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-3-(4-(2-methoxyphenyl)piperazin-1-yl)propanamide

SMILES COc1cccc2C(CCCc12)NC(=O)CCN1CCN(CC1)c1ccccc1OC

InChI Key InChIKey=HGOXUQUWFDSTAA-UHFFFAOYSA-N

Data  5 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50052563   

TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50052563(N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-3-...)
Affinity DataIC50: 761nMAssay Description:In vitro inhibition of [3H]spiroperidol binding to rat Dopamine D2 receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50052563(N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-3-...)
Affinity DataIC50: 38nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to rat 5-HT 1a receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50052563(N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-3-...)
Affinity DataIC50: 38nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in rat hippocampus membranes using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50052563(N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-3-...)
Affinity DataIC50: 761nMAssay Description:Binding affinity against Dopamine receptor D2 in rat striatal membrane using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50052563(N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-3-...)
Affinity DataKi:  67nMAssay Description:Displacement of [3H]YM-09151-2 from human Dopamine receptor D4.2 expressed in baculovirus Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50052563(N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-3-...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50052563(N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-3-...)
Affinity DataKi:  253nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Wistar Han rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50052563(N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-3-...)
Affinity DataKi:  253nMAssay Description:Displacement of [3H]spiperone from Dopamine receptor D2 of rat corpora striata synaptic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50052563(N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-3-...)
Affinity DataKi:  269nMAssay Description:Displacement of [3H]LSD from rat recombinant 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed