BDBM50052473 1,8-Dihydroxy-10-(3-methoxy-phenylsulfanyl)-10H-anthracen-9-one::CHEMBL323497

SMILES COc1cccc(SC2c3cccc(O)c3C(=O)c3c(O)cccc23)c1

InChI Key InChIKey=JPXSVEIHSYRVAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052473   

Target5-lipoxygenase(Bovine)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052473(1,8-Dihydroxy-10-(3-methoxy-phenylsulfanyl)-10H-an...)
Affinity DataIC50: 1.50E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mouse)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052473(1,8-Dihydroxy-10-(3-methoxy-phenylsulfanyl)-10H-an...)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed