BDBM50052469 (4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-ylsulfanyl)-acetic acid methyl ester::CHEMBL107734

SMILES COC(=O)CSC1c2cccc(O)c2C(=O)c2c(O)cccc12

InChI Key InChIKey=RZFYIGVCTVZWAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052469   

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mouse)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052469((4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-yls...)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052469((4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-yls...)
Affinity DataIC50: 1.30E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed