BDBM50052449 10-Benzylsulfanyl-1,8-dihydroxy-10H-anthracen-9-one::CHEMBL106514

SMILES Oc1cccc2C(SCc3ccccc3)c3cccc(O)c3C(=O)c12

InChI Key InChIKey=SVCCMVDKTSCNNB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50052449   

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mouse)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052449(10-Benzylsulfanyl-1,8-dihydroxy-10H-anthracen-9-on...)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052449(10-Benzylsulfanyl-1,8-dihydroxy-10H-anthracen-9-on...)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052449(10-Benzylsulfanyl-1,8-dihydroxy-10H-anthracen-9-on...)
Affinity DataIC50: 3.00E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed