BDBM50052428 2-(2,6-Dioxo-piperidin-3-yl)-4,5,6,7-tetrafluoro-isoindole-1,3-dione::CHEMBL11440

SMILES Fc1c2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c(F)c(F)c1F

InChI Key InChIKey=PIJMHCCGPUSELZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052428   

TargetTumor necrosis factor(Human)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50052428(2-(2,6-Dioxo-piperidin-3-yl)-4,5,6,7-tetrafluoro-i...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against TNF-alpha productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50052428(2-(2,6-Dioxo-piperidin-3-yl)-4,5,6,7-tetrafluoro-i...)
Affinity DataKi:  6.08E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed