BDBM50052380 2,4-Dimethyl-6-phenyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester::CHEMBL100071

SMILES CCOC(=O)C1C(C)C(C(=O)OCC)=C(N=C1C)c1ccccc1

InChI Key InChIKey=BDQQHLSPSKHQHY-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50052380   

TargetAdenosine receptor A3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50052380(2,4-Dimethyl-6-phenyl-1,4-dihydro-pyridine-3,5-dic...)
Affinity DataKi:  7.24E+3nMAssay Description:Displacement of [125]AB-MECA binding to human Adenosine A3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50052380(2,4-Dimethyl-6-phenyl-1,4-dihydro-pyridine-3,5-dic...)
Affinity DataKi:  7.24E+3nMAssay Description:Displacement of [125]AB-MECA binding to human Adenosine A3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50052380(2,4-Dimethyl-6-phenyl-1,4-dihydro-pyridine-3,5-dic...)
Affinity DataKi:  7.24E+3nMAssay Description:Binding affinity against cloned human adenosine A3 receptor by radioligand binding assay using [125I]-AB-MECA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50052380(2,4-Dimethyl-6-phenyl-1,4-dihydro-pyridine-3,5-dic...)
Affinity DataKi:  7.24E+3nMAssay Description:Displacement of [125I]AB-MECA from adenosine A3 receptor from HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50052380(2,4-Dimethyl-6-phenyl-1,4-dihydro-pyridine-3,5-dic...)
Affinity DataKi:  2.59E+4nMAssay Description:Displacement of [3H](R)-PIA binding to Adenosine A1 receptor in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50052380(2,4-Dimethyl-6-phenyl-1,4-dihydro-pyridine-3,5-dic...)
Affinity DataKi:  2.59E+4nMAssay Description:Displacement of [3H](R)-PIA binding to Adenosine A1 receptor in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50052380(2,4-Dimethyl-6-phenyl-1,4-dihydro-pyridine-3,5-dic...)
Affinity DataKi:  2.59E+4nMAssay Description:Binding affinity against adenosine A1 receptor in rat cerebral cortex membrane by radioligand binding assay using [3H](R)-PIA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50052380(2,4-Dimethyl-6-phenyl-1,4-dihydro-pyridine-3,5-dic...)
Affinity DataKi:  2.59E+4nMAssay Description:Binding affinity for adenosine A1 receptor as displacement of [3H]R-PIA from rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50052380(2,4-Dimethyl-6-phenyl-1,4-dihydro-pyridine-3,5-dic...)
Affinity DataKi:  3.59E+4nMAssay Description:Displacement of [3H]-CGS- 21680 binding to Adenosine A2A receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50052380(2,4-Dimethyl-6-phenyl-1,4-dihydro-pyridine-3,5-dic...)
Affinity DataKi:  3.59E+4nMAssay Description:Displacement of [3H]-CGS- 21680 binding to Adenosine A2A receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50052380(2,4-Dimethyl-6-phenyl-1,4-dihydro-pyridine-3,5-dic...)
Affinity DataKi:  3.59E+4nMAssay Description:Displacement of [3H]-CGS- 21680 from Adenosine A2A receptor of rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50052380(2,4-Dimethyl-6-phenyl-1,4-dihydro-pyridine-3,5-dic...)
Affinity DataKi:  3.59E+4nMAssay Description:Binding affinity for adenosine A2A receptor as displacement of [3H]-CGS- 21680 from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed