BDBM50052090 6,7-Dimethoxy-9-(3,4,5-trimethoxy-phenyl)-3H-naphtho[2,3-c]furan-1-one::CHEMBL284006

SMILES COc1cc(cc(OC)c1OC)-c1c2C(=O)OCc2cc2cc(OC)c(OC)cc12

InChI Key InChIKey=VFULRIWYLLHLAZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50052090   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Tan£Be Seiyaku

Curated by ChEMBL
LigandPNGBDBM50052090(6,7-Dimethoxy-9-(3,4,5-trimethoxy-phenyl)-3H-napht...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition in vitro of Phosphodiesterase 5 isolated from guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Dog)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50052090(6,7-Dimethoxy-9-(3,4,5-trimethoxy-phenyl)-3H-napht...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50052090(6,7-Dimethoxy-9-(3,4,5-trimethoxy-phenyl)-3H-napht...)
Affinity DataIC50: 820nMAssay Description:Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50052090(6,7-Dimethoxy-9-(3,4,5-trimethoxy-phenyl)-3H-napht...)
Affinity DataIC50: 320nMAssay Description:Inhibitory activity against phosphodiesterase 3 (PDE 3) isolated from cardiac ventricleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed