BDBM50051985 CHEMBL288826::N-[3-(4-Benzyl-piperidin-1-yl)-propyl]-2,2-diphenyl-acetamide

SMILES O=C(NCCCN1CCC(Cc2ccccc2)CC1)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=DKXNWXXUHISEHY-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50051985   

TargetSodium channel protein type 2 subunit alpha(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051985(N-[3-(4-Benzyl-piperidin-1-yl)-propyl]-2,2-dipheny...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50051985(N-[3-(4-Benzyl-piperidin-1-yl)-propyl]-2,2-dipheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]-5-hydroxytryptamine reuptake in human SERT expressed in HEK293 cells by microbeta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2019
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50051985(N-[3-(4-Benzyl-piperidin-1-yl)-propyl]-2,2-dipheny...)
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of [3H]-5-norepinephrine reuptake in human NET expressed in HEK293 cells by microbeta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2019
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50051985(N-[3-(4-Benzyl-piperidin-1-yl)-propyl]-2,2-dipheny...)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of [3H]-5-dopamine reuptake in human DAT expressed in HEK293 cells by microbeta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2019
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50051985(N-[3-(4-Benzyl-piperidin-1-yl)-propyl]-2,2-dipheny...)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of [3H]dopamine uptake at DAT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50051985(N-[3-(4-Benzyl-piperidin-1-yl)-propyl]-2,2-dipheny...)
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of [3H]norepinephrine uptake at NET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50051985(N-[3-(4-Benzyl-piperidin-1-yl)-propyl]-2,2-dipheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]serotonin uptake at SERT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed