BDBM50051957 CHEMBL3322566

SMILES COc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(=O)NCCN5CCCC5)c4C)C(=O)Nc3c2)cc1

InChI Key InChIKey=HYDSSXBBNYALNP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50051957   

TargetAurora kinase B(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051957(CHEMBL3322566)
Affinity DataIC50: 93nMAssay Description:Inhibition of Aurora B (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051957(CHEMBL3322566)
Affinity DataIC50: 1nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051957(CHEMBL3322566)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051957(CHEMBL3322566)
Affinity DataIC50: 21nMAssay Description:Inhibition of VEGFR2 (unknown origin) using poly[Glu:Tyr] substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051957(CHEMBL3322566)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Flt3 (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051957(CHEMBL3322566)
Affinity DataIC50: 11nMAssay Description:Inhibition of c-Met (unknown origin) using KKKSPGEYVNIEFG substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed