BDBM50051941 CHEMBL3322565

SMILES COc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(O)=O)c4C)C(=O)Nc3c2)cc1

InChI Key InChIKey=LFKPJUFFMOTFRX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50051941   

TargetAurora kinase A(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051941(CHEMBL3322565)
Affinity DataIC50: 203nMAssay Description:Inhibition of Aurora A (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetAurora kinase B(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051941(CHEMBL3322565)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of Aurora B (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetAurora kinase C(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051941(CHEMBL3322565)
Affinity DataIC50: 154nMAssay Description:Inhibition of Aurora C (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051941(CHEMBL3322565)
Affinity DataIC50: 1nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051941(CHEMBL3322565)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051941(CHEMBL3322565)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of Flt3 (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051941(CHEMBL3322565)
Affinity DataIC50: 31nMAssay Description:Inhibition of c-Met (unknown origin) using KKKSPGEYVNIEFG substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed