BDBM50051939 CHEMBL3322590

SMILES Fc1ccccc1-c1c[nH]cc(C(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)c1=O

InChI Key InChIKey=QBOWGZQRUNUQGL-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50051939   

TargetCytochrome P450 1A2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin) using 3-Cyano-7-ethoxycoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50: 40nMAssay Description:Inhibition of CYP2C9 (unknown origin) using Vivid OOMR substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin) using 3-Cyano-7-ethoxycoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin) using 3-Cyano-7-ethoxycoumarin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using Vivid OOMR substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG channel by hERG Tracer Red based fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50: 100nMAssay Description:Inhibition of Flt3 (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetAurora kinase B(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50: 26nMAssay Description:Inhibition of Aurora B (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed