BDBM50051922 (R)-4-Amino-5-{4-[(2,4-diamino-pyrido[2,3-d]pyrimidin-6-ylamino)-methyl]-benzoylamino}-5-oxo-pentanoic acid::CHEMBL33045

SMILES N[C@H](CCC(O)=O)C(=O)NC(=O)c1ccc(CNc2cnc3nc(N)nc(N)c3c2)cc1

InChI Key InChIKey=ULAKSKJGSNQDHB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50051922   

TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051922((R)-4-Amino-5-{4-[(2,4-diamino-pyrido[2,3-d]pyrimi...)
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against recombinant ec dihydrofolate reductase(in 50 uM dihydrofolic acid)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051922((R)-4-Amino-5-{4-[(2,4-diamino-pyrido[2,3-d]pyrimi...)
Affinity DataIC50: 67nMAssay Description:Inhibitory activity against recombinant lc dihydrofolate reductase(in 50 uM dihydrofolic acid)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051922((R)-4-Amino-5-{4-[(2,4-diamino-pyrido[2,3-d]pyrimi...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against recombinant sf dihydrofolate reductase(in 50 uM dihydrofolic acid)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051922((R)-4-Amino-5-{4-[(2,4-diamino-pyrido[2,3-d]pyrimi...)
Affinity DataIC50: 320nMAssay Description:Inhibitory activity against recombinant human dihydrofolate reductase(in 50 uM dihydrofolic acid)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed