BDBM50051832 CHEMBL440280::[((2E,6E,10E)-3,7,11,15-Tetramethyl-hexadeca-2,6,10,14-tetraenyloxycarbamoyl)-methyl]-phosphonic acid

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#8]-[#7]-[#6](=O)-[#6]P([#8])([#8])=O

InChI Key InChIKey=JXSRQDGLMQBUPI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50051832   

LigandPNGBDBM50051832([((2E,6E,10E)-3,7,11,15-Tetramethyl-hexadeca-2,6,1...)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of farnesylation of P21ras protein in human PC-3 prostate cancer cell line by proliferation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50051832([((2E,6E,10E)-3,7,11,15-Tetramethyl-hexadeca-2,6,1...)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of geranylgeranylation of P21rap in human PC-3 prostate cancer cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50051832([((2E,6E,10E)-3,7,11,15-Tetramethyl-hexadeca-2,6,1...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of farnesylation of P21ras in human PC-3 prostate cancer cells by immunoprecipitation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50051832([((2E,6E,10E)-3,7,11,15-Tetramethyl-hexadeca-2,6,1...)
Affinity DataIC50: 3.50E+3nMAssay Description:In vitro inhibition of farnesyl protein transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50051832([((2E,6E,10E)-3,7,11,15-Tetramethyl-hexadeca-2,6,1...)
Affinity DataIC50: 66nMAssay Description:In vitro inhibition of Geranylgeranyl protein transferase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed