BDBM50051831 CHEMBL26146::[((2E,6E,10E)-3,7,11,15-Tetramethyl-hexadeca-2,6,10,14-tetraenyloxycarbamoyl)-methyl]-phosphonic acid monoethyl ester

SMILES [#6]-[#6]-[#8]P([#8])(=O)[#6]-[#6](=O)-[#7]-[#8]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6]

InChI Key InChIKey=BIUZXEXLTICOBX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50051831   

LigandPNGBDBM50051831([((2E,6E,10E)-3,7,11,15-Tetramethyl-hexadeca-2,6,1...)
Affinity DataIC50: 4.02E+4nMAssay Description:Inhibition of geranylgeranylation of P21rap in human PC-3 prostate cancer cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50051831([((2E,6E,10E)-3,7,11,15-Tetramethyl-hexadeca-2,6,1...)
Affinity DataIC50: 3.51E+4nMAssay Description:Inhibition of farnesylation of P21ras protein in human PC-3 prostate cancer cell line by proliferation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50051831([((2E,6E,10E)-3,7,11,15-Tetramethyl-hexadeca-2,6,1...)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of farnesylation of P21ras in human PC-3 prostate cancer cells by immunoprecipitation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed