BDBM50051818 CHEMBL3318333

SMILES Cc1ccc(cc1)-n1nnnc1C\C=N\Nc1ccc(Cl)cc1

InChI Key InChIKey=PPAOBOHNCAUWEH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50051818   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50051818(CHEMBL3318333)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins in presence of 5 mM GSH by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50051818(CHEMBL3318333)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50051818(CHEMBL3318333)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins in presence of 0.01% Triton-X by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50051818(CHEMBL3318333)
Affinity DataIC50: 340nMAssay Description:Inhibition of mouse IDO1 expressed in mouse P815B cells using L-tryptophan substrate incubated for 18 hrs by HPLC based cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50051818(CHEMBL3318333)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells using L-tryptophan substrate incubated for 24 hrs by HPLC based cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed