BDBM50051751 1-[3-(4-Isopropenyl-phenyl)-8-aza-bicyclo[3.2.1]oct-2-yl]-propan-1-one::CHEMBL85877

SMILES CCC(=O)C1C2CCC(CC1c1ccc(cc1)C(C)=C)N2

InChI Key

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50051751   

TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50051751(1-[3-(4-Isopropenyl-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]RTI-55 from dopamine transporter of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50051751(1-[3-(4-Isopropenyl-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50051751(1-[3-(4-Isopropenyl-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataKi:  94nMAssay Description:Displacement of [3H]-nisoxatine from Norepinephrine transporter of rat forebrain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed