BDBM50051607 CHEMBL3337526::US11071729, Compound 19

SMILES CC(C)Cn1ccc(N2CCC(CC2)c2ccccc2)c(Cl)c1=O

InChI Key InChIKey=JDKWNHPOHQWVSN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50051607   

TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50051607(CHEMBL3337526 | US11071729, Compound 19)
Affinity DataEC50:  195nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50051607(CHEMBL3337526 | US11071729, Compound 19)
Affinity DataEC50:  195nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2022
Entry Details
Go to US Patent