BDBM50051591 CHEMBL3337525::US11071729, Compound 4

SMILES FC(F)(F)c1c(ccn(CC2CC2)c1=O)N1CCC(CC1)c1ccccc1

InChI Key InChIKey=UTDUPZRTTJVHAB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50051591   

TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50051591(CHEMBL3337525 | US11071729, Compound 4)
Affinity DataEC50:  251nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50051591(CHEMBL3337525 | US11071729, Compound 4)
Affinity DataEC50:  355nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2022
Entry Details
Go to US Patent