BDBM50051515 CHEMBL80698::[(2S,3aS,7aS)-2-(Pyrrolidine-1-carbonyl)-octahydro-indol-1-yl]-((1R,2S)-2-thiophen-2-yl-cyclopropyl)-methanone

SMILES O=C([C@@H]1C[C@@H]1c1cccs1)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)N1CCCC1

InChI Key InChIKey=AAYJVJWHJJTTDQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051515   

TargetProlyl endopeptidase(Rat)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50051515([(2S,3aS,7aS)-2-(Pyrrolidine-1-carbonyl)-octahydro...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity was evaluated against Post-proline cleaving enzyme from rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed