BDBM50051350 2,3-Dihydro-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one::2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one::4'-Hydroxyflavanone::CHEMBL73933

SMILES c1ccc2c(c1)C(=O)C[C@H](O2)c3ccc(cc3)O

InChI Key InChIKey=ZLHVIYHWWQYJID-UHFFFAOYSA-N

Data  4 KI  3 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50051350   

TargetXanthine dehydrogenase/oxidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50051350(2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one |...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50051350(2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one |...)
Affinity DataIC50: 5.75E+4nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)TBA
LigandPNGBDBM50051350(2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one |...)
Affinity DataIC50: 145nMAssay Description:Inhibition of AchE in Rattus norvegicus (rat) cortex homogenates by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50051350(2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one |...)
Affinity DataKi:  1.15E+4nMAssay Description:Ability to displace [3H]N6-phenylisopropyladenosine binding from adenosine A1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50051350(2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one |...)
Affinity DataKi:  1.15E+4nMAssay Description:Binding affinity at Adenosine A1 receptor in rat brain membranes by [3H]PIA displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50051350(2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one |...)
Affinity DataKi:  2.29E+4nMAssay Description:Ability to displace [125I]-AB-MECA binding from adenosine A3 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50051350(2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one |...)
Affinity DataKi:  4.28E+4nMAssay Description:Binding affinity against human adenosine A3 receptor in HEK293 cells using [125I]AB-MECA 21680 radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed