BDBM50051242 8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine::8-butyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine::CHEMBL16894

SMILES CCCCn1cc2c(n1)nc(N)n1nc(nc21)-c1ccco1

InChI Key InChIKey=NSGXVWJIQHDYOE-UHFFFAOYSA-N

Data  14 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50051242   

TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50051242(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]tria...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-SCH- 58261 from human adenosine A2A receptor expressed in CHO cells; range 1.4-2.1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50051242(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]tria...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50051242(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]tria...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of [3H]-CGS- 21680 binding to Adenosine A2A receptor in rat striatal homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50051242(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]tria...)
Affinity DataKi:  2.40nMAssay Description:Binding ability of adenosine A2a receptor by using [3H]-CGS- as radioligand in rat striatal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50051242(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]tria...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells; range 11-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50051242(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]tria...)
Affinity DataKi:  30.4nMAssay Description:Inhibition of [3H]-CHA binding to Adenosine A1 receptor in rat whole brain homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50051242(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]tria...)
Affinity DataKi:  30.4nMAssay Description:Binding ability of adenosine A1 receptor by using [3H]CHA as radioligand in rat whole brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50051242(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]tria...)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]DPCPX from Adenosine A2b receptor expressed in CHO cells; range 40-69More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50051242(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]tria...)
Affinity DataKi:  600nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells; range 525-691More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50051242(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]tria...)
Affinity DataKi:  600nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50051242(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]tria...)
Affinity DataKi:  600nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50051242(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]tria...)
Affinity DataKi:  600nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50051242(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]tria...)
Affinity DataKi:  600nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50051242(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]tria...)
Affinity DataKi:  6.03E+5nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed