BDBM50051215 (3-Nitro-phenyl)-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester::CHEMBL279617

SMILES [O-][N+](=O)c1cccc(NC(=O)OCCCc2cnc[nH]2)c1

InChI Key InChIKey=IXZVARDZBBMVPA-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50051215   

TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50051215((3-Nitro-phenyl)-carbamic acid 3-(1H-imidazol-4-yl...)
Affinity DataKi:  19.9nMAssay Description:Binding affinity against Histamine H3 receptor on Synaptosomes from rat cerebral cortex was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50051215((3-Nitro-phenyl)-carbamic acid 3-(1H-imidazol-4-yl...)
Affinity DataKi:  22nMAssay Description:In vitro antagonistic activity against Histamine H3 receptor on Synaptosomes of rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50051215((3-Nitro-phenyl)-carbamic acid 3-(1H-imidazol-4-yl...)
Affinity DataKi:  1.26E+4nMAssay Description:Binding affinity against H1 receptor of Guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Guinea pig)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50051215((3-Nitro-phenyl)-carbamic acid 3-(1H-imidazol-4-yl...)
Affinity DataKi:  1.26E+4nMAssay Description:Binding affinity against H2 receptor of Guinea pig atriumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed