BDBM50051153 CHEMBL14128::{(R)-2,4,8-Trioxo-7-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-methyl]-1,4,7,8-tetrahydro-2H-pyrido[3,4-d]pyrimidin-3-yl}-acetic acid methyl ester

SMILES COC(=O)Cn1c(=O)[nH]c2c(ccn(CC(=O)NC(C(C)C)C(=O)C(F)(F)F)c2=O)c1=O

InChI Key InChIKey=ULZFZBUSHMTYQC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051153   

TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051153({(R)-2,4,8-Trioxo-7-[(3,3,3-trifluoro-1-isopropyl-...)
Affinity DataKi:  490nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed