BDBM50051139 CHEMBL13863::N-(3,3,3-Trifluoro-1-isopropyl-2-oxo-propyl)-2-((R)-2,4,8-trioxo-6-phenyl-2,3,4,8-tetrahydro-1H-pyrido[3,4-d]pyrimidin-7-yl)-acetamide

SMILES CC(C)C(NC(=O)Cn1c(cc2c([nH]c(=O)[nH]c2=O)c1=O)-c1ccccc1)C(=O)C(F)(F)F

InChI Key InChIKey=ZNHHLURDTJYWSY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051139   

TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051139(N-(3,3,3-Trifluoro-1-isopropyl-2-oxo-propyl)-2-((R...)
Affinity DataKi:  15nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed