BDBM50050999 (2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-[(diisobutylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL266354

SMILES COc1ccc(cc1)[C@@H]1[C@H]([C@@H](CN1CC(=O)N(CC(C)C)CC(C)C)c1ccc2OCOc2c1)C(O)=O

InChI Key InChIKey=VTCRAOPUDXFWQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050999   

TargetEndothelin receptor type B(Pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050999((2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-[(diisobutylc...)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibitory activity measured against Endothelin B receptor binding to porcine cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050999((2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-[(diisobutylc...)
Affinity DataIC50: 16.2nMAssay Description:Inhibitory activity against the Endothelin A receptor of rat MMQ cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed