BDBM50050675 CHEMBL33650::[(S)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=LRRMIZSGLAPKAB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50050675   

TargetNeuromedin-K receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50050675([(S)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2...)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibitory activity against binding of [125I][MePhe7]-NKB SP to tachykinin NK-3 receptor in guinea pig cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50050675([(S)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [125I][MePhe]-NKB binding to human Tachykinin receptor 3 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50050675([(S)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2...)
Affinity DataIC50: 1.55E+3nMAssay Description:Tested for binding affinity for human NK3 receptor expressed in CHO cells by using [125I][MePhe]-NKB as radioligand,More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50050675([(S)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2...)
Affinity DataIC50: 1.60E+3nMAssay Description:Binding affinity towards Tachykinin receptor 3 using [125I]-[Mephe7] NKB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50050675([(S)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2...)
Affinity DataIC50: 1.50E+3nMAssay Description:Compound was tested for binding affinity against human Tachykinin receptor 3 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50050675([(S)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2...)
Affinity DataIC50: 1.55E+3nMAssay Description:Compound was tested for the inhibition of [125I]-[MePhe7]-NKB binding to cloned human Tachykinin receptor 3 in CHO cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed