BDBM50050591 7-Methyl-2-(2-propoxy-phenyl)-3H-thieno[3,2-d]pyrimidin-4-one::CHEMBL46639

SMILES CCCOc1ccccc1-c1nc2c(C)csc2c(=O)[nH]1

InChI Key InChIKey=HGFSMFHLDNRFTM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050591   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050591(7-Methyl-2-(2-propoxy-phenyl)-3H-thieno[3,2-d]pyri...)
Affinity DataIC50: 80nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050591(7-Methyl-2-(2-propoxy-phenyl)-3H-thieno[3,2-d]pyri...)
Affinity DataEC50:  1.50E+3nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed