BDBM50049806 CHEMBL127969::Thiophene-2-carboxylic acid [2-(1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)-ethyl]-amide

SMILES CN1C(CCNC(=O)c2cccs2)CN=C(c2ccccc2)c2ccccc12

InChI Key InChIKey=PYCHFYLMMMZMSJ-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50049806   

TargetKappa-type opioid receptor(Guinea pig)
Universitá

Curated by ChEMBL
LigandPNGBDBM50049806(Thiophene-2-carboxylic acid [2-(1-methyl-5-phenyl-...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity against Opioid receptor kappa 1 of guinea pig using [3H]U-65693 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Universitá

Curated by ChEMBL
LigandPNGBDBM50049806(Thiophene-2-carboxylic acid [2-(1-methyl-5-phenyl-...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50049806(Thiophene-2-carboxylic acid [2-(1-methyl-5-phenyl-...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Universitá

Curated by ChEMBL
LigandPNGBDBM50049806(Thiophene-2-carboxylic acid [2-(1-methyl-5-phenyl-...)
Affinity DataKi:  6.40nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Universitá

Curated by ChEMBL
LigandPNGBDBM50049806(Thiophene-2-carboxylic acid [2-(1-methyl-5-phenyl-...)
Affinity DataKi:  6.40nMAssay Description:Binding affinity of compound was determined against Opioid receptor mu 1 from native receptor in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50049806(Thiophene-2-carboxylic acid [2-(1-methyl-5-phenyl-...)
Affinity DataKi:  9.40nMAssay Description:Binding affinity determined against Opioid receptor mu 1 from human cloned receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50049806(Thiophene-2-carboxylic acid [2-(1-methyl-5-phenyl-...)
Affinity DataKi:  94nMAssay Description:Binding affinity determined against Opioid receptor delta 1 from human cloned receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50049806(Thiophene-2-carboxylic acid [2-(1-methyl-5-phenyl-...)
Affinity DataKi:  105nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H]DADLE as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50049806(Thiophene-2-carboxylic acid [2-(1-methyl-5-phenyl-...)
Affinity DataKi:  105nMAssay Description:Binding affinity of compound was determined against Opioid receptor delta 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Universitá

Curated by ChEMBL
LigandPNGBDBM50049806(Thiophene-2-carboxylic acid [2-(1-methyl-5-phenyl-...)
Affinity DataKi:  1.30E+4nMAssay Description:Binding affinity against Cholecystokinin type B receptor using [3H](MeNLE28,31)-CCK-8 as radioligand in guinea pig cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed