BDBM50049422 CHEMBL3315335

SMILES CC(C)C[C@H](NC(=O)CCC1CCCCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(N)=O

InChI Key InChIKey=GXEWWEPRKCMGJF-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50049422   

TargetNeuromedin-U receptor 2(Human)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50049422(CHEMBL3315335)
Affinity DataEC50:  6.40nMAssay Description:Agonist activity at human NMUR2 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetNeuromedin-U receptor 2(Human)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50049422(CHEMBL3315335)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at human NMUR2 expressed in HEK293 cells assessed as induction of IP3 levels using myo-[2-3H(N)]-inositol after 60 mins by SPA-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 2(Human)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50049422(CHEMBL3315335)
Affinity DataIC50: 44nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR2 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50049422(CHEMBL3315335)
Affinity DataIC50: 4.29E+3nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 2(Human)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50049422(CHEMBL3315335)
Affinity DataEC50:  6.40nMAssay Description:Agonist activity at human NMUR2 expressed in CHO cells by Fluo-4-AM dye based calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed