BDBM50049297 7-ethyl-7-hydroxy-14-(1-pyridiniumylmethyl)-(7S)-7,8,11,13-tetrahydro-10H-[1,3]dioxolo[5,4-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11-dione::CHEMBL162904

SMILES CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc5OCOc5cc4c(C[n+]4ccccc4)c3Cn1c2=O

InChI Key InChIKey=ITDYGAOQYQOVGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049297   

TargetDNA topoisomerase 1(Human)
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049297(7-ethyl-7-hydroxy-14-(1-pyridiniumylmethyl)-(7S)-7...)
Affinity DataIC50: 210nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed