BDBM50049292 8-ethyl-8-hydroxy-15-pyrazin-1-ium-1-ylmethyl-(8S)-2,3,8,9,12,14-hexahydro-11H-[1,4]dioxino[3,2-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-9,12-dione::CHEMBL350118

SMILES CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc5OCCOc5cc4c(C[n+]4ccncc4)c3Cn1c2=O

InChI Key InChIKey=SXEKZVUTWLJFNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049292   

TargetDNA topoisomerase 1(Human)
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049292(8-ethyl-8-hydroxy-15-pyrazin-1-ium-1-ylmethyl-(8S)...)
Affinity DataIC50: 180nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-1 isolated from calf thymusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed