BDBM50049257 Azepan-(2Z)-ylideneamine::CHEMBL315857::CHEMBL543752

SMILES NC1=NCCCCC1

InChI Key InChIKey=GTLJSJNKRLFVSJ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50049257   

TargetNitric oxide synthase, endothelial(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(CHEMBL543752 | CHEMBL315857 | Azepan-(2Z)-ylidenea...)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(CHEMBL543752 | CHEMBL315857 | Azepan-(2Z)-ylidenea...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory activity against Neuronal nitric oxide synthase at 100 uM concentration was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(CHEMBL543752 | CHEMBL315857 | Azepan-(2Z)-ylidenea...)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(CHEMBL543752 | CHEMBL315857 | Azepan-(2Z)-ylidenea...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(CHEMBL543752 | CHEMBL315857 | Azepan-(2Z)-ylidenea...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(CHEMBL543752 | CHEMBL315857 | Azepan-(2Z)-ylidenea...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049257(CHEMBL543752 | CHEMBL315857 | Azepan-(2Z)-ylidenea...)
Affinity DataIC50: 5.40E+4nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(CHEMBL543752 | CHEMBL315857 | Azepan-(2Z)-ylidenea...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(CHEMBL543752 | CHEMBL315857 | Azepan-(2Z)-ylidenea...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(CHEMBL543752 | CHEMBL315857 | Azepan-(2Z)-ylidenea...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human endothelia constitutive enzyme (Endothelial nitric oxide synthase) and partially pur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed