BDBM50049254 (2S)-2-amino-5-(N-methylcarbamimidamido)pentanoic acid::CHEMBL99636::N(5)-carbamimidoyl-N(5)-methyl-L-ornithine::N(5)-methyl-L-arginine::delta-N-methylarginine

SMILES CN(CCC[C@H](N)C(O)=O)C(N)=N

InChI Key InChIKey=XKCWNEVAXQCMGP-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50049254   

TargetNitric oxide synthase, inducible(Mouse)
Université

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Compound was evaluated for inhibitory activity against iNOS obtained from RAW 264.7 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory activity against human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of human recombinant DDAH1 expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human recombinant eNOS by griess assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human recombinant nNOS by griess assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human recombinant iNOS by griess assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataKi:  1.40E+6nMAssay Description:Binding affinity towards inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed