BDBM50049196 3-[3-Bromo-2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-5-pentafluoroethyl-2-propyl-3H-imidazole-4-carboxylic acid::CHEMBL291803

SMILES CCCc1nc(c(C(O)=O)n1Cc1ccc(cc1Br)-c1ccccc1-c1nnn[nH]1)C(F)(F)C(F)(F)F

InChI Key InChIKey=VCEBXZBLTUKCPY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049196   

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50049196(3-[3-Bromo-2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Affinity DataIC50: 80nMAssay Description:Compound was tested for the inhibition of angiotensin II AT2 receptor by displacement of [125I]- Ang II to rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50049196(3-[3-Bromo-2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Affinity DataIC50: 80nMAssay Description:Inhibitory activity at Angiotensin II type 2 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
LigandPNGBDBM50049196(3-[3-Bromo-2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article