BDBM50048618 CHEMBL3319622

SMILES CC1(C)CCc2cc(ccc2O1)S(=O)(=O)N(CC(O)=O)Cc1ccc(Oc2ccc(cn2)C(F)(F)F)cc1

InChI Key InChIKey=SJMLZXITFYDBMT-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50048618   

TargetDiacylglycerol lipase-alpha(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50048618(CHEMBL3319622)
Affinity DataIC50: 65nMAssay Description:Inhibition of human DAGLalpha expressed in HEK293T cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50048618(CHEMBL3319622)
Affinity DataIC50: 743nMAssay Description:Inhibition of MB064 labeling of DAGLalpha in mouse brain homogenates by activity based protein profiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50048618(CHEMBL3319622)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of human ABHD6 expressed in HEK293T cell membranes assessed as reduction in glycerol production using 2-arachidonoyl glycerol substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed