BDBM50048569 8-(3-Fluoro-propyl)-3-(4-iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid isopropyl ester::CHEMBL345760

SMILES CC(C)OC(=O)C1C2CCC(CC1c1ccc(I)cc1)N2CCCF

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50048569   

TargetSodium-dependent dopamine transporter(Rat)
Research Biochemicals International

Curated by ChEMBL
LigandPNGBDBM50048569(8-(3-Fluoro-propyl)-3-(4-iodo-phenyl)-8-aza-bicycl...)
Affinity DataKi:  1.20nMAssay Description:In vitro binding affinity towards dopamine transporter in rat striatal membranes by [3H]GBR-12395 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Biochemicals International

Curated by ChEMBL
LigandPNGBDBM50048569(8-(3-Fluoro-propyl)-3-(4-iodo-phenyl)-8-aza-bicycl...)
Affinity DataKi:  49nMAssay Description:In vitro binding affinity towards serotonin transporter in rat cerebral cortical homogenates by [3H]paroxetine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Biochemicals International

Curated by ChEMBL
LigandPNGBDBM50048569(8-(3-Fluoro-propyl)-3-(4-iodo-phenyl)-8-aza-bicycl...)
Affinity DataKi:  1.00E+4nMAssay Description:In vitro binding affinity towards Norepinephrine transporter rat cerebral cortical homogenates by [3H]nisoxetine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed