BDBM50048568 8-(2,2-Difluoro-ethyl)-3-(4-iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL356166

SMILES COC(=O)C1C2CCC(CC1c1ccc(I)cc1)N2CC(F)F

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50048568   

TargetSodium-dependent serotonin transporter(Rat)
Research Biochemicals International

Curated by ChEMBL
LigandPNGBDBM50048568(8-(2,2-Difluoro-ethyl)-3-(4-iodo-phenyl)-8-aza-bic...)
Affinity DataKi:  9.60nMAssay Description:In vitro binding affinity towards serotonin transporter in rat cerebral cortical homogenates by [3H]paroxetine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Biochemicals International

Curated by ChEMBL
LigandPNGBDBM50048568(8-(2,2-Difluoro-ethyl)-3-(4-iodo-phenyl)-8-aza-bic...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity towards dopamine transporter in rat striatal membranes by [3H]GBR-12395 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Biochemicals International

Curated by ChEMBL
LigandPNGBDBM50048568(8-(2,2-Difluoro-ethyl)-3-(4-iodo-phenyl)-8-aza-bic...)
Affinity DataKi: >5.00E+3nMAssay Description:In vitro binding affinity towards Norepinephrine transporter rat cerebral cortical homogenates by [3H]nisoxetine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed